Sonowell

SonoWell®

SonoWell® represents the latest evolution of Inno-Sol’s technology, developed through extensive design and validation with the support of Italian universities. It is the first commercially available all-in-one ultrasound system specifically designed for experimental applications on cells and tissue samples.

Designed for biologists in biomedical research, SonoWell® is a configurable, modular, and expandable integrated device that enables ultrasound experiments using standard well plates from 6 to 96 wells. With a single set-up, it manages programming, temperature control, sample movement, ultrasound delivery, and data analysis. This integrated approach ensures flexible experimental design and produces accurate, homogeneous, reproducible, and comparable results.

Flexibility

Configurable from 1 to 4 transducers, also at different frequencies, which can simultaneously sonicate on different wells, using common commercial plates up to 96 wells, with a frequency range from 500 kHz to 5 MHz, and making it possible to compare the frequency effect in experiments conducted on the same plate. Inno-Sol’s Patented Technology allows different frequency transducers to share the same Near/Far Field plane.

Compactness

Inside a compact 40 × 40 × 40 cm rack, easily placed on a laboratory benchtop, shelf, or cart, SonoWell® houses the ultrasonic frequency generator, amplifier, and fluidic control unit. Separate warm and cold circuits manage sample thermostating and transducer cooling, with pumps and 10 µm filters for particle removal and degassing. Quick-release connectors simplify filter replacement, while the entire process is programmed and controlled through the SonoWell Soft© software.

Accuracy and Ease of Use

The entire experimental workflow is managed by the proprietary software SonoWell Soft©. Featuring a user-friendly, multi-window graphical interface, it allows researchers to program all experimental parameters and protocols, even offline. Users can configure one to four transducers operating independently, select the plate type, define ultrasound emission parameters such as frequency, intensity, sonication time, duty cycle, and repetition frequency for each well, and set synchronized plate movement paths. Offline programmability on different Windows PCs allows multiple researchers or teams to share the instrument efficiently, using machine time only for experiment execution and significantly improving laboratory productivity and flexibility.

Precision

The plates containing the biological samples are immersed in the thermostating tank and moved by high-precision stepper motor systems (2.5µm step), controlled by the System and programmed via SonoWell Soft©. The thermostating tank, the transducer holder, and the precision plate movement mechanics are structurally integral, therefore sharing the reference system of the coordinates and guaranteeing the perfect orthogonality of the axes and planes of the transducers.
For further information, please contact us at: amministrazione@inno-sol.it